Macrolide resistance mediated by a Bifidobacterium breve membrane protein.

نویسندگان

  • Abelardo Margolles
  • José Antonio Moreno
  • Douwe van Sinderen
  • Clara G de Los Reyes-Gavilán
چکیده

A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 10  شماره 

صفحات  -

تاریخ انتشار 2005